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Dapoxetine CAS 129938-20-1 Androgenic Anabolic Steroids Muscle Gain Supplements

Dapoxetine CAS 129938-20-1 Androgenic Anabolic Steroids Muscle Gain Supplements

Brand Name : YIHAN
Model Number : Dapoxetine
Certification : GMP,SGS,ISO,KOSHER
Place of Origin : China
Payment Terms : Western Union, L/C, D/A, D/P, T/T, MoneyGram
Supply Ability : 5000kg/ month
Delivery Time : Within 24hours after receiving the payment
Packaging Details : Very discreet or as required
Product Name : Dapoxetine
CAS No : 129938-20-1
Appearance : White powder
Assay : 99%
Usage : Pharmaceutical Intermediates
MW : 341.88
Mf : C21h23no HCl
Grade Standard : Medicine Standard
MOQ : Negotiation
Price : Negotiation
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Dapoxetine CAS 129938-20-1 Androgenic Anabolic Steroids Muscle Gain Supplements


Quick Detail:
Dapoxetine is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.

Product name: Dapoxetine hydrochloride
Alias: Dapoxetine hydrochloride; Dapoxetine; Dapoxetine hcl
CAS No: 129938-20-1
MF: C21H23NO. HCl
MW: 341.88
Usage : pharmaceutical raw materials, the hormone
Assay: 99%
Brand: HKYC
Packaging Details: Foil bag or as requirement
Payment Terms: T/T, Western Union, MoneyGram
Shipping way: EMS, HKEMS, DHL, TNT, Fedex, UPS (you can choose the fastest and your favourite)

Description :

Dapoxetine (dapoxetine) as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders

Applications :

Randomized, double blind, placebo-controlled trials have confirmed the efficacy of dapoxetine for the treatment of PE. Different dosage has different impacts on different type of PE. Dapoxetine 60 mg significantly improves the mean intravaginal ejaculation latency time (IELT) compared to that of dapoxetine 30 mg in men with lifelong PE, but there is no difference in men with acquired PE. Dapoxetine, given 1-3 hours before sexual episode, prolongs IELT, increases the sense of control and sexual satisfaction in men of 18 to 64 years of age with PE.

Since PE is associated with personal distress, interrelationship difficulty, dapoxetine provides help for men with PE to overcome this condition. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used.

Spefication:


Items of analysis
SpecificationResults
CharacteristicsWhite or almost white crystalline powderWhite crystalline powder
Melting point175.0~177.0ºC176.0ºC
Specific rotatlon+128°±3(C=1,CH3OH)+128°±3(C=1,CH3OH)
Loss on drying≤0.5%0.32%
Heavy metals0ppm0ppm
Relative substanceTotal impurity≤0.1%0.07%
Assay(on dried basis)≥99.5%99.61%
ConclusionIt complies to enterprise standard

Application:


Dapoxetine, marketed as (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 1864 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.
Treat male premature ejaculation and erectile dysfunction. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.


Specification:



ITEMS

STANDARD

RESULTS

Appearance

White to off-white powder

White powder

Identification

IR & H-NMR

H-NMR

Melting point

180°C ~ 184°C

181.2°C ~ 182°C

Loss on drying

≤0.5 %

0.3%

Residue on ignition

≤0.01%

Conforms

Heavy Metals

≤10ppm

8ppm

Specific Ratation

[α] D20+128° ±3° (C=1, CH3OH)

+127.6

Total impurities

≤1.0%

0.21%

Purity

≥99.0% ~101.0%

99.46%

Our Advantage:

1, High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity≥ 99%
3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

3, We have clients throughout the world.

1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.


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